Over-the-top comedy starring Tracey Ullman as Sylvia Stickles, a wife and mother living in Baltimore who, along with her husband Vaughn (Chris Isaak) and mother Big Ethel (Suzanne Shepherd), operates a local convenience store. One day, Sylvia receives a sharp blow to the head, which leaves her with a concussion. However, the concussion comes with an unexpected side effect - Sylvia has suddenly become a sex addict, and is soon attended to by the perverse and lascivious sexual evangelist Ray-Ray (Johnny Knoxville). When it becomes evident that Vaughn can’t keep up with her sensual appetites, Sylvia throws herself into the strange netherworld of Baltimore’s community of erotic overachievers, which includes her daughter Caprice (Selma Blair), who is living a double life as uber-buxom exotic entertainer Ursula Udders.